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Pancreatic endocrine tumor or pancreatic neuroendocrine tumor refers to the development of the tumors resulting from the abnormal growth of the hormone-producing or endocrine cells in the pancreas known as islet cells. Pancreatic endocrine tumor accounts for the 7% of all pancreatic tumors and can be malignant or benign and often grow slower than the exocrine tumors. Pancreatic endocrine can be either functional (hormone-producing) or non-functional (no hormone-producing).
Based on the type of the hormone produced by the pancreatic endocrine tumor, these tumors can cause a variety of symptoms such as stomach ulcers, severe diarrhea, diabetes, hypoglycemia, gallstones, and acromegaly. Some of the various types of pancreatic endocrine tumors include insulinomas, somatostatinomas, glucagonomas, VIPomas and gastrinomas. Most of the strategies for the treatment and management of the pancreatic endocrine tumors centers around a combination approach of several therapeutic measures. Treatment options include surgical removal of the tumors, chemotherapy, radiation therapy and hormone therapy.
Pharmaceutical companies along with various research institutes have been focusing on studying and developing new treatment options for pancreatic endocrine tumor. For instance; CVM-1118, which is being studied by TaiRx, Inc., is currently in phase-2 clinical trials for the study of safety, tolerability, and efficacy of CVM-1118 in patients with the pancreatic neuroendocrine tumor.
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At present more than 80% of the pipeline candidates for pancreatic endocrine tumor are in the phase-1 and phase-2 stage. Majority of the studies are sponsored by universities and academic research institutes.
The report on ‘Pancreatic Endocrine Tumor– Pipeline Review, 2019’ provides a comprehensive overview of the drugs that are in the R&D pipeline by indication or molecule for Pancreatic Endocrine Tumor. The report provides a thorough analysis of the distribution of the pipeline products by clinical trial stage, indication, company, therapy area and details such as clinical trial stage, sponsor, description on every product in the pipeline. Products in the preclinical and clinical stage along with dormant & discontinued pipeline candidates are included in the report. The report also covers additional insights such as epidemiology overview and current market scenario for Pancreatic Endocrine Tumor.
The report on ‘Pancreatic Endocrine Tumor – Pipeline Review, 2019’, which is built by following a robust research methodology involving primary interviews and desk research, provides a complete overview of the R&D activity and pipeline products to assist companies in developing growth strategies and identifying emerging players.
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