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Lymphocyte activation gene 3 protein is one of the important checkpoints in defense mechanism which is present on the surface of effector T cells and regulatory T cells. These special types of proteins play a prominent role in functioning and controlling of effector and regulatory T cells in order to create an immune response to foreign cells. Lymphocyte Activation Gene 3 (LAG 3) protein is one of the important prognostic indicators of inadequate treatment outcomes of chronic lymphocytic leukemia, moreover, it plays a modulating role in autoimmune diabetes.
Pharmaceutical companies and academic centers & research institutes are prominently focusing on studying and developing new treatment options for the Lymphocyte Activation Gene 3 Protein. For instance; XmAb22841, which is being studied by Xencor, is currently in phase-1 clinical trials to check its efficacy and tolerability for the treatment of gastrointestinal stromal tumors (GIST) and neuroendocrine tumors (NET). However, in preclinical studies, XmAb18087 has shown its potential in the stimulation of target-dependent T-cell activation.
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At present around 99% of the pipeline candidates for lymphocyte activation gene 3 protein are in the phase-1 and phase-2 stage. Currently, there is no molecule available in phase 3 and phase 4. Majority of the studies have been sponsored by pharmaceutical companies and research institutes & academic centers.
The report on ‘Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) – Pipeline Review, 2019’ provides a comprehensive overview of the drugs that are in the R&D pipeline by indication or molecule for Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3). The report provides a thorough analysis of the distribution of the pipeline products by clinical trial stage, indication, company, therapy area and details such as clinical trial stage, sponsor, description on every product in the pipeline. Products in the preclinical and clinical stage along with dormant & discontinued pipeline candidates are included in the report. The report also covers additional insights such as epidemiology overview and current market scenario for Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3).
The report on ‘Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) – Pipeline Review, 2019’, which is built by following a robust research methodology involving primary interviews and desk research, provides a complete overview of the R&D activity and pipeline products to assist companies in developing growth strategies and identifying emerging players.
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