Anti-obesity Drugs Market Size, Share & Industry Analysis, By Type (Prescription Drugs and OTC Drugs), By Distribution Channel (Hospital Pharmacy and Retail and Online Pharmacy), and Regional Forecast, 2024-2032

The global anti-obesity drugs market size was valued at USD 4.51 billion in 2023 and is projected to grow from USD 6.15 billion in 2024 to USD 37.94 billion by 2032, exhibiting a CAGR of 25.5% during the forecast period (2024-2032). Moreover, the U.S. anti-obesity drugs market size is projected to grow significantly, reaching an estimated value of USD 23.60 billion by 2032, driven by improved adoption rate due to increasing prevalence of comorbidities.

As per World Health Organization (WHO), overweight and obesity are defined as abnormal or excessive accumulation of fat that increases the risk of other chronic diseases such as insulin resistance, glucose intolerance, hypertension, sleep apnea, diabetes mellitus, arthritis, gall bladder diseases, and certain types of cancers. The significant rise in the prevalence rate of obesity has led to a large patient population suffering from debilitating and chronic conditions that severely affect the patient's daily functioning and have severe implications on their mortality.

According to the a 2023 estimate by the Centers for Disease Control and Prevention (CDC), more than 684,000 obesity-associated cancers occur in the U.S. each year, of which more than 210,000 are men and 470,000 are women. Further, it stated that breast cancer is the most common obesity-associated cancer among women, whereas it is colorectal cancer among men. Creating more awareness of the dangers of this chronic disease and the high healthcare expenditure associated with it, especially among the younger generation, will lead to the greater adoption of therapeutics for early and preventive care of the disease. All these factors are anticipated to drive the growth of the market over the forecast period.

Furthermore, the COVID-19 pandemic negatively influenced the market growth. The expansion was hampered in 2020 due to a reduction of in-person visits to healthcare professionals and the shutdown of non-essential healthcare services. In 2021, the increasing use of telemedicine in place of ‘in-person’ hospital visits and the utilization of online pharmacies to procure repeat medications minimized the adverse impact on the market. The market experienced growth post-pandemic with ease of COVID-19 regulations and increased prevalence rate of obesity across the globe. In 2023, the market was expected to witness substantial growth attributed to new product launches, the promising pipeline of prominent companies. These factors are expected to propel the growth of market during the forecast period.

Anti-obesity Drugs Market Trends

Increasing Awareness Regarding Obesity Treatment Creating Growth Opportunities in the Market

Over the past few decades, the prevalence rate of obesity has significantly increased, and it is now considered an epidemic. Obesity constitutes a severe public health problem, as it substantially increases the risk of chronic diseases such as type 2 diabetes, cardiovascular disease, blood pressure, and certain cancers. This has raised the awareness level among the population regarding severe chronic disease, which can be avoided by following appropriate action plans, including the following:

• In March 2023, the World Obesity Federation started a new campaign on obesity under the name “Changing Perspectives: Let’s Talk About Obesity” on the occasion of World Obesity Day with an aim to correct misconceptions with constructive communication and pave the way toward a healthier future.

Such initiatives made by international organizations and strict implementation will increase awareness regarding disease conditions. Several industry players developing and engaged in launches of effective therapeutics are strategically endorsing their products to tackle the problem, propelling the growth of the anti-obesity drugs market during the forecast period.

• In June 2023, Retatrutide, an investigational drug of Eli Lilly Company with the potential to treat obesity and type 2 diabetes and is suitable for once in a week injection. These diabetes drugs work by appetite suppression to induce weight loss.

Anti-obesity Drugs Market Growth Factors

Increasing Prevalence of Obesity to Boost the Expansion of the Market

The prevalence of obesity has radically increased in all regions of the world, but the rate varies significantly by country due to sedentary lifestyle trends and unhealthy diets. Even though there is no direct correlation between obesity rate and the economic status of a country, it has been observed that wealthier countries tend to implement more programs, campaigns, and initiatives to raise awareness and education among people about healthy lifestyles.

• In March 2023, the World Obesity Federation published an article stating that 4.0 billion people globally are anticipated to live with obesity by 2035 if measures are not taken in current stage.

In terms of the impact on society as a whole, it has significant direct and indirect cost implications, which place considerable strain on healthcare and social resources. Some European countries most affected by this “obesity epidemic” include Malta, Hungary, and Lithuania.

• According to the World Obesity Atlas 2023, published by World Obesity Federation in March 2023, obesity and overweight will have economic impact globally and the number is going to surpass USD 4.32 trillion annually by 2035.

Additionally, in Asian countries the prevalence of obesity is expected to grow at a substantially higher rate. It is estimated that India and Pakistan will have highest prevalence of obesity among adults by 2035.

Increasing Pipeline Drugs for Obesity by Market Players to Propel the Growth of the Market during the Forecast Period

Globally, obesity has reached epidemic proportions, and as per WHO data, at least 2.8 million people are dying each year due to this problem. This increase in the prevalence of obesity will significantly increase the demand for effective therapeutic measures to combat the disease. As the problem of obesity is anticipated to grow over the next few decades, the need for the launch of new anti-obesity drugs in the global market will be greater. This has led several prominent and emerging companies to be engaged in R&D initiatives for the development of anti-obesity drugs to fulfill the demand.

• In May 2023, Innovent Biologics, Inc.’s phase 2 clinical study of mazdutide (IBI362) with a higher dose of 9 mg achieved positive outcomes in Chinese adults with obesity. Such developments in R&D reflect a great potential for future product launches.

RESTRAINING FACTORS

Stringent Drug Approval Policies May Limit the Market Growth Prospects

Despite the increased need for effective anti-obesity drugs, the stringent regulatory scenario is one of the substantial hindrances to market growth. There is considerable difficulty in the regulatory process for the approval of new anti-obesity drugs, which may prevent many established biopharmaceutical companies from investing in this market. Moreover, it also increases their R&D expenses and limits revenue growth, impacting the scope for new product launches and restraining market growth.

• The European Medicines Agency (EMA) has issued regulatory approvals for only three drug therapies (orlistat, bupropion/naltrexone, and liraglutide) in contrast to the U.S. FDA’s approval of five drug therapies. For instance, many regulatory bodies utilize a guideline of 5.0% total weight loss to determine whether a drug induces a significant weight loss. Such stringent regulatory requirements significantly hamper the global anti-obesity drugs market growth.

Anti-obesity Drugs Market Segmentation Analysis

By Type Analysis

Prescription Drugs Segment Dominates the Market Due to Increasing Adoption of Obesity Management Products

Based on type, the global market is segmented into prescription drugs and over-the-counter (OTC) drugs.

According to global anti-obesity drugs market analysis the prescription drugs segment dominated market with the highest market share in 2023 due to the presence of key market players with regulatory approvals for their products. These companies are driving the adoption of these products by increasing investment in R&D initiatives and strategic partnerships to introduce effective treatments. Additionally, increasing prescriptions from healthcare professionals are boosting the sales of prescription drugs, and expected launches of prescription drugs during forecast period resulting in the segment’s dominance in the global market.

Furthermore, increasing initiatives for the easy procurement of the anti-obesity drugs by key market players leads to the growth of the prescription segment during the forecast period.

• For instance, in January 2024, Eli Lilly announced the launch of new website named LillyDirect with an aim to improve access of patients for weight loss drug Zepbound, through telehealth. Such initiatives lead to increase the growth of the market.

The OTC drugs segment is estimated to grow at a lower CAGR due to limited product offerings. Some other factors pertaining to the lower CAGR include personal concerns associated with adverse side effects after the consumption of OTC drugs, restricting the segment’s growth during the forecast period.

By Distribution Channel Analysis

Growing Accessibility for Drugs is projected to Drive the Retail and Online Pharmacy Segment

Based on distribution channel, the market is classified into hospital pharmacy, retail, and online pharmacy.

The retail and online pharmacy segment dominated the global anti-obesity drugs market share is projected to generate the highest revenue in the global market in 2023 due to increasing usage of e-pharmacies platforms and the availability of anti-obesity drugs on these platforms, making drug procurement procedure easier for the patient population. Furthermore, obesity is a chronic condition, and the patient needs a refill to continue the long-term treatment plan leading to greater adoption of anti-obesity drugs through retail and online pharmacy distribution channels.

The hospital pharmacy segment is anticipated to grow with a lower CAGR during the forecast period. Despite the need for a prescription for medicines from trained professionals, the hospital segment is anticipated to witness slower growth due to the presence of alternative distribution channels for the procurement of anti-obesity drugs, which provide treatment at affordable costs and at a convenient time.

REGIONAL INSIGHTS

Based on region, the global market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.

The North America held the largest share of the market and was valued at USD 3.01 billion in 2023 and is likely to remain dominant over the forecast period. The growth in this region is attributed to the strong prevalence of obesity across the region and comprises high-income countries with high healthcare expenditure per person. As per a study published by the National Library of Medicine in 2021, the annual medical care costs are high at USD 2,505 for adults with obesity in the U.S. and increase significantly with the class of obesity from 68.4% for class 1 to 233.6% for class 3.

Europe is expected to be the second leading region in terms of revenue, attributable to the presence of strong market players, including Novo Nordisk A/S, across the region with increasing investments in R&D activities for the launch of new products.

• According to United Nations, the cost related to obesity and overweight in all age groups is projected to cost USD 800 billion for WHO European region by 2035.

Moreover, Asia Pacific is estimated to showcase a comparatively higher CAGR due to the rising prevalence of obesity and the comorbidities associated with this condition, as there is a strong relationship between the number of comorbidities and obesity.

• According to the World Obesity Atlas 2023 report, published by the World Obesity Federation, out of ten countries with greatest increase in obesity globally, nine are from Asia and Africa. Such rising prevalence of obesity in the region, surges the adoption of these products.

On the other hand, Latin America and the Middle East & Africa are estimated to grow at a comparatively lower CAGR due to lack of well-established healthcare infrastructure compared to other regions. These regions accounted for a smaller market share in 2023 as the healthcare expenditure per person is low and there is limited awareness of these products in these regions. These factors lower the adoption rate of drugs, leading to slower growth in these regions.

List of Key Companies in Anti-obesity Drugs Market

Novo Nordisk A/S Dominates the Market Due to Strong Product Portfolio

In terms of the competitive landscape, the market is consolidated, with a few market players holding a major share of the market. Currently, Novo Nordisk A/S holds a peak market position owing to a strong product portfolio and recent product approvals by various regulatory agencies, which support the company's growth. In June 2021, Novo Nordisk A/S received the U.S. Food and Drug Administration (U.S. FDA) approval for Wegovy, which is indicated for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidities. Additionally, the company announced that the sales of the obesity medication, Wegovy will be more in 2024 compared to 2023. These factors, coupled with strong product sales across various regions, account for the company’s dominance in the market. GlaxoSmithKline plc is also one of the key players on account of its over-the-counter anti-obesity drug called Alli.

Other prominent players included in the market include Novartis AG, VIVUS LLC., Currax Pharmaceuticals LLC, and others. The strong focus of companies on strategic initiatives and new advanced product launches is fueling the market growth.

LIST OF KEY COMPANIES PROFILED:

• Novo Nordisk A/S (Denmark)


• GlaxoSmithKline plc (U.K.)


• VIVUS LLC. (U.S.)


• Currax Pharmaceuticals LLC (U.S.)


• F. Hoffmann-La Roche Ltd (Switzerland)


• Pfizer Inc. (U.S.)


• Sandoz International GmbH (Novartis AG) (Germany)


• Boehringer Ingelheim International GmbH (Germany)

KEY INDUSTRY DEVELOPMENTS:

• November 2023: Lilly announced the approval of Zepbound by the U.S. Food and Drug Administration for managing chronic weight in adults with obesity.


• October 2022: Lilly received Fast Track Designation from USFDA for tirzepatide. The product is being studied for the treatment of obesity, or overweight in adults.


• February 2022: Pfizer Inc.’s study on oral diabetes medication called glucagon-like peptide-1 receptors showed that the medication could help control type 2 diabetes and contribute to weight loss as obesity is often tied to type 2 diabetes.


• November 2021: Novo Nordisk announced that the European regulatory authority, Committee for Medicinal Products for Human Use (CHMP), adopted a positive opinion and recommended the marketing authorization for Wegovy for chronic weight management in adults with obesity.


• October 2021: Navamedic ASA extended its distribution rights for Mysimba in the Nordics. In 2017, Navamedic ASA secured exclusive distribution rights of Mysimba in the Nordics for five years from Currax Pharmaceutical LLC, previously known as Orexigen Therapeutics, Inc.


• April 2021: Zealand Pharma A/S and Boehringer Ingelheim initiated Phase 2 trials of the GLP-1/glucagon dual agonist BI 456906 for overweight or obese adults and for non-alcoholic steatohepatitis (NASH) adults.

REPORT COVERAGE

The global anti-obesity drugs market report provides qualitative and quantitative insights on the global market and a detailed analysis of global market size & growth rate for all possible segments in the market. Along with this, the report provides an elaborative analysis of the global market dynamics and competitive landscape. Various key insights presented in the report are the prevalence of obesity – for key countries/regions, new product launches, key recent industry developments – mergers, acquisitions, and partnerships, - pipeline analysis and impact of COVID-19 on the global market.

Report Scope & Segmentation